Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
  • Users Online: 241
  • Home
  • Print this page
  • Email this page
ORIGINAL ARTICLE
Year : 2017  |  Volume : 16  |  Issue : 2  |  Page : 103-110

Relationship of second-to-fourth digit ratio with metabolic syndrome indices and serum biomarkers in Hausa ethnic group of Kano, Nigeria


1 Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Bayero University, Kano, Kano State, Nigeria
2 Department of Human Anatomy, Faculty of Medicine, Ahmadu Bello University, Zaria, Nigeria
3 Department of Chemical Pathology, Faculty of Medicine, Ahmadu Bello University, Zaria, Nigeria

Correspondence Address:
Dr. Abdullahi Yusuf Asuku
Department of Anatomy, Faculty of Basic Medical Sciences, College of Health Sciences, Bayero University, Kano, P. M. B. 3011, Kano State
Nigeria
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/jeca.jeca_24_17

Rights and Permissions

BACKGROUND: High prevalence levels of the metabolic syndrome (MetS) in developed and developing countries and the associated high mortality and morbidity are forcing scientists to explore promising therapeutic agents and population-specific anthropometric criteria for defining its phenotype. OBJECTIVES: The aim of this study is to investigate the relationship between digit length and second-to-fourth digit ratio (2D:4D) with the indices of MetS and its serum biomarkers. MATERIAL AND METHODS: The study was a cross-sectional study which included 465 (266 males and 199 females) Hausas of Kano, with a mean age of 34.4 years and 32.0 years for males and females, respectively. Systematic random sampling technique was employed for subject recruitment. Height, weight, waist circumference, body mass index, and digit lengths were obtained using standard protocol. Overnight fasting blood sample was obtained for fasting blood glucose, high density lipoprotein cholesterol (HDL-c), total cholesterol, triglycerides, low-density lipoprotein, uric acid, and adiponectin estimation using standard laboratory protocols. Blood pressure was measured following standard clinical procedure. Pearson's correlation was used to test the association between the digit lengths, 2D:4D with MetS indices, uric acid, and adiponectin. To compare between-group parameters of males and females, left and right hand, Student's t-test and one-way ANOVA were used. SPSS version 20 software was used for statistical analyses and P < 0.05 was set as level of significance. RESULTS: 2D:4D showed significant positive correlation with uric acid, blood pressure, and serum parameters of MetS. A negative correlation was observed between 2D:4D, adiponectin, and HDL. In both sexes, the R2D:4D had stronger correlation with MetS indicators when compared with the L2D:4D. CONCLUSION: 2D:4D is good correlate of metabolic risk parameters and R2D:4D correlates better than L2D:4D.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed59    
    Printed11    
    Emailed0    
    PDF Downloaded20    
    Comments [Add]    

Recommend this journal